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  1. Metformin / Pioglitazone Dosage Guide + Max Dose, Adjustments …

    • Individualize dose based on safety, efficacy, and prior therapy 1. All doses provided as pioglitazone/metformin 1. For patients inadequately control on metformin monotherapy: May initiate with 15 mg… See more

    Liver Dose Adjustments

    Avoid use in patients with clinical or laboratory evidence of hepatic disease Liver function … See more

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    Dose Adjustments

    Elderly: Renal function should be assessed more frequently in elderly patients. New York Heart Association (NYHA) Class I or Class II Heart Failure: 1. Initial dose (IR): pioglitazon… See more

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    Precautions

    US BOXED WARNING(S): Congestive Heart Failure and Lactic Acidosis: 1. CONGESTIVE HEART FAILURE: Thiazolidinediones, including pioglitazone, may cause … See more

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    Other Comments

    Administration advice: 1. Take with food 2. Swallow whole with a glass of water 3. Extended-release product should not be chewed, cut, or crushed; the tablet shell may be see… See more

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  1. Pioglitazone and metformin (oral route) - Mayo Clinic

  2. Metformin and pioglitazone Uses, Side Effects & Warnings

  3. Metformin/pioglitazone: Side Effects, Dosage, Uses, …

    Jan 26, 2018 · Use your current dosage of metformin and pioglitazone. Maximum dosage: 2,550 mg metformin/45 mg pioglitazone per day. It’s taken as 850 mg metformin/15 mg pioglitazone three times...

  4. Pioglitazone-Metformin - Uses, Side Effects, and More

    Take this medication by mouth as directed by your doctor, usually once or twice daily with meals to decrease stomach upset. Drink plenty of fluids while taking this medication unless otherwise...

  5. Actoplus Met: Uses, Dosage & Side Effects - Drugs.com

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  7. Pioglitazone and Metformin: Dosage, …

    Feb 10, 2020 · Dosage adjustment with strong CYP2C8 inhibitors (eg, gemfibrozil): Maximum recommended dose: Pioglitazone 15 mg and metformin 850 mg daily (immediate release) or pioglitazone 15 mg/metformin 1 g daily …

  8. Initial management of hyperglycemia in adults with type 2 …