Zhang lab @ MIT & Broad
WEBZhang lab @ MIT & Broad. Biological Discovery & Engineering. Image credit to Steph Stevens (2023) We explore and study biological diversity to understand nature and discover systems and processes that may be harnessed through bioengineering for the improvement of human well-being. Recent Highlights. Strucutral insights into the mechanism of Fanzor.
Guide design resources - Zhang Lab
WEBBroad Institute Programmable Therapeutics Gift Donors. Kenneth C. Griffin. James & Patricia Poitras. Asness Family Foundation. The Milky Way Research Foundation. K. Lisa Yang Brain-Body Center at MIT. David Cheng. 75 Ames Street, Cambridge, MA 02142. zhang@broadinstitute.org.
Zhang Lab
WEBWe use light to study biochemical signals in living neurons, brain tissues, and behaving animals. We customize hardware and software solutions to overcome experimental challenges. We tinker, improve, and collaborate.
The Yang Zhang Lab
WEBLigand Docking and Structure-Based Drug Design. Determining structure and function of protein molecules is a cornerstone of modern biology and medicine. One of the main focuses of our lab is to develop computational methods to predict 3-dimensional structure of protein molecules from amino acid sequence, and to deduce the biological functions ...
the Zhang Lab
WEBOver the last decade, the Zhang lab has made significant contributions to the epigenetic field by identifying and characterizing many chromatin modifying enzymes that include: 1) the nucleosome remodeling and deacetylase NuRD ; 2) the H3K27me3 methyltransferase PRC2 (Science 2002); 3) the ubiquitin E3 ligase PRC1 (Nature 2004); 4) the JmjC ...
Zhang Lab
WEBThe Zhang lab studies fundamental mechanisms of brain development with the ultimate goal of diagnosing and treating neurological disorders. Our current research centers on: Neurogenesis in the cerebral cortex: The six-layered neocortex is …
Zhang Lab
WEBAug 11, 2022 · Zhang Lab. A number of cellular therapeutics and tools for cellular modulation have been developed, such as RNAi and CRISPR-based technologies, providing avenues for genome and transcriptome engineering.
Research - Zhang Lab
WEBResearch — Zhang Lab. We are thinking about a number of problems, including new approaches for precision gene editing, delivery of molecular and genetic cargo, discovery of novel programmable systems, and engineering of the immune system to develop the next generation of therapeutics.
the PI — the Zhang Lab
WEBthe PI — the Zhang Lab. Dr. Yi Zhang. Yi Zhang is currently an Investigator of the Howard Hughes Medical Institute, and the Fred Rosen Chair Professor of Genetics at Harvard Medical School and Boston Children’s Hospital.
Welcome to Zhang Lab | Zhang Lab
WEBDana-Farber Cancer Institute and Harvard Medical Schools Zhang Lab studies the molecular pathogenesis of diffused large B cell lymphoma and EBV-associated B cell lymphoma to identify the surveillance mechanism of the immune system on tumors and develop strategies to harness immune cells for tumor therapy.