The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

Antibodies are secreted immunoglobulin molecules produced mainly by plasma cells. The antigen-binding site of the antibody has a unique structure that allows it to bind antigen in a highly ...

Arbele inks collaboration with BioAI Health to develop prototype of immunohistochemistry based quantification algorithm: Seattle Friday, October 11, 2024, 16:00 Hrs [IST] Arbele, ...

Arbele, a leading innovator in biopharmaceutical & biotechnology focused on targeting cadherin-17 (CDH17), is pleased to announce strategic collaborations in precision oncology using artificial ...

Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary ...

Mizuno, Hirashima and Toda use E-cadherin and P-cadherin in the current study ... in which the extracellular domain of Notch is replaced by an antibody or nanobody and the intracellular domain by an ...

By engineering gene expression responsive to artificial morphogens, we observe that coupling morphogen signals with cadherin-based adhesion is sufficient to convert a morphogen gradient into distinct ...

Conjugated antibodies can theoretically achieve this ... including the folate receptor (FR) alpha, cadherin 6 (CDH6), human epidermal growth factor receptor 2 (HER-2), TROP-2, and NaPi2b.

Monoclonal antibodies -- treatments developed by cloning a cell that makes an antibody -- could help provide an answer to the growing problem of antimicrobial resistance, say scientists.

Both GDNF and US-CM upregulated claudin-5 and VE-cadherin expression, which were attenuated by anti-GDNF antibody and GDNF signaling inhibitors. GDNF increased claudin-5 expression via the ...