We also have available humanized G551D CFTR (hG551D) rats that are sensitive to ivacaftor therapy and G542X CFTR rats that are subject to nonsense-mediated decay. Sharma J, et al: A novel G542X CFTR ...
We prepared slides containing an oligonucleotide probe (P1) specific for a 39-base sequence adjacent to the G542X locus of the CFTR gene. The probe contained a free 5´ phosphate, and was bound ...
FABP-hCFTR-G542X mice: Express a human CFTR-G542X transgene from the intestine-specific FABP promoter on the Cftr tm1Cam FABP-hCFTR-W1282X mice: Express a human CFTR-W1282X transgene from the ...