CX3C chemokine receptor 1 (CX3CR1) is a G protein-coupled receptor that may be a useful marker of Eomes+ Th cells; the antigen has been shown to be expressed by cytotoxic Th cells and required for ...

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an ...

In parallel, the protective barrier macrophages (CX3CR1+) were depleted in established RA, showing a switch in the dominance of joint macrophages from protective macrophages to pro-inflammatory ...

1). “Among the dominant cytotoxic cells identified in COVID-19 patients, cells known to be regulated by the fractalkine system (CX3CR1/L1) are prominent. Blood concentration of the ligand ...

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an ...

Following placement of skin allografts, donor DCs, often referred to as passenger leukocytes, migrate out of the graft through lymphatic vessels and infiltrate the recipient's draining lymph nodes ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

A new study proposes a better understanding of the site of inflammation in RA which will allow for the development of new treatment strategies or predictive biomarkers which could support the ...