The assessment of cAMP with the homogeneous time-resolved fluorescence (HTRF) kits allows the implementation of functional assays to screen new drug candidates in high-throughput screening (HTS ...
The assay uses antibodies that selectively bind cGAMP in the presence of excess ATP and GTP. When the fluorescent tracer is displaced by cGAMP, a change in signal is achieved. The novel direct ...
The new assay measures the enzymatic activity of cyclic GMP-AMP synthase (cGAS) by directly detecting the product cGAMP, in a simple mix-and-read format. Based on the proven Transcreener platform, ...