Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic (B ...

Figure 1: The transcriptional control of late B-cell differentiation. Figure 2: Model of the interaction of BLIMP1 and IL-2 in T-cell differentiation. Although it is still early days in our ...

Elicera Therapeutics describes how CAR T cells armed with neutrophil-activatingprotein can improve cancer therapy by inducing ...

The following is a summary of “Altered B-cell, plasma cell and antibody immune profiles in blood of systemic mastocytosis,” ...

"We really focus on one function of B-cells, which is the activation of CD8 T-cells," a specialized type of defensive immune cell which are tailored to fight specific pathogens. In the current ...

Inflammatory processes are the body’s defence against local damage and disease. Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with ...

There are different types of lymphocytes. The 2 main types are T lymphocytes (T cells) and B lymphocytes (B cells). PTCL develops when the body makes abnormal T cells. So it is a type of T cell ...

Specifically, the genes dictate the visibility of epitopes, or proteins that ... A gene mutation causing cells to go rogue isn’t as rare as you might think, says Kornelia Polyak, a molecular ...

Phase I clinical trial with a first-generation combination of two HER-2 chimeric B-cell MVF 316–339 epitopes and MVF 628–647 [169–171] emulsified with nor-MDP as adjuvant and ISA 720 vehicle ...

The double-negative CD4–CD8 cells and CAR T cells then outgrew other populations. Panel B shows an alluvial plot that summarizes the evolution of the cellular composition from the creation of ...

'Promiscuous' T-cell epitopes offer the best alternative in the design of chimeric vaccines able to function as potential cancer vaccines. Peptide mimics must also be designed to adopt ...